• Published 2005

Running title : Gut endocrine cells operate under immune control 1 Immune control of food intake : enteroendocrine cells are regulated by CD 4 + T-lymphocytes during small intestinal inflammation

@inproceedings{McDermott2005RunningT,
  title={Running title : Gut endocrine cells operate under immune control 1 Immune control of food intake : enteroendocrine cells are regulated by CD 4 + T-lymphocytes during small intestinal inflammation},
  author={Jacqueline R. McDermott and Fiona Leslie and Massimo D'Amato and David G. Thompson and Richard K. Grencis and John T. McLaughlin},
  year={2005}
}
Background and aims: Gastrointestinal inflammation reduces food intake, but the biological mechanisms explaining suppressed feeding during inflammation are unknown. We have used a model of upper gut infection (Trichinella spiralis in the mouse) to study the effect of inflammation on food intake, and explored the role of a key enteroendocrine cell (EEC) in the regulation of feeding by the immune response. Methods: Food intake of NIH mice infected with the intestinal nematode Trichinella spiralis… CONTINUE READING

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