Running performance and cardiovascular capacity are not impaired in creatine-depleted rats.

@article{Adams1995RunningPA,
  title={Running performance and cardiovascular capacity are not impaired in creatine-depleted rats.},
  author={Gregory R. Adams and Paul W Bodell and Kenneth M. Baldwin},
  journal={Journal of applied physiology},
  year={1995},
  volume={79 3},
  pages={1002-7}
}
Several published reports have indicated that derangement of the phosphocreatine/creatine (Cr) energy-buffering system via Cr analogue feeding results in cardiomyopathy when cardiac performance is assessed in vitro. The present study was designed to examine indexes of cardiac performance in rats that have been chronically Cr depleted. Adult (180 +/- 4 g) rats were assigned to a normal diet (ND) (n = 8) or a Cr-depletion diet (CD) group (n = 10). After 61 +/- 1 days of ad libitum feeding… CONTINUE READING
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