Running-induced epigenetic and gene expression changes in the adolescent brain.

  title={Running-induced epigenetic and gene expression changes in the adolescent brain.},
  author={Jean LeBeau Abel and Emilie F. Rissman},
  journal={International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience},
  volume={31 6},
Physical exercise is associated with positive neural functioning. Here we examined the gene expression consequences of 1 week of voluntary wheel running in adolescent male mice. We assayed expression levels of genes associated with synaptic plasticity, signaling pathways, and epigenetic modifying enzymes. Two regions were examined: the hippocampus, which is typically examined in exercise studies, and the cerebellum, an area directly involved in motor control and learning. After 1 week of… CONTINUE READING
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