Rumen epithelial adaptation to high-grain diets involves the coordinated regulation of genes involved in cholesterol homeostasis.

@article{Steele2011RumenEA,
  title={Rumen epithelial adaptation to high-grain diets involves the coordinated regulation of genes involved in cholesterol homeostasis.},
  author={Michael A Steele and Gordon Vandervoort and Ousama Alzahal and Sarah E. Hook and James C Matthews and Brian W Mcbride},
  journal={Physiological genomics},
  year={2011},
  volume={43 6},
  pages={308-16}
}
The molecular mechanisms underlying rumen epithelial adaption to high-grain (HG) diets are unknown. To gain insight into the metabolic mechanisms governing epithelial adaptation, mature nonlactating dairy cattle (n = 4) were transitioned from a high-forage diet (HF, 0% grain) to an HG diet (65% grain). After the cattle were fed the HG diet for 3 wk, they returned to the original HF diet, which they were fed for an additional 3 wk. Continuous ruminal pH, ruminal short chain fatty acids, and… CONTINUE READING