Rules Governing Selective Protein Carbonylation

  title={Rules Governing Selective Protein Carbonylation},
  author={Etienne Maisonneuve and Adrien Ducret and Pierre H. Khoueiry and Sabrina Lignon and Sonia Longhi and E. Talla and Sam Dukan},
  booktitle={PloS one},
BACKGROUND Carbonyl derivatives are mainly formed by direct metal-catalysed oxidation (MCO) attacks on the amino-acid side chains of proline, arginine, lysine and threonine residues. For reasons unknown, only some proteins are prone to carbonylation. METHODOLOGY/PRINCIPAL FINDINGS we used mass spectrometry analysis to identify carbonylated sites in: BSA… CONTINUE READING