Ruled by waves? Intracellular and intercellular calcium signalling.

  title={Ruled by waves? Intracellular and intercellular calcium signalling.},
  author={J A R\ottingen and Jens Gustav Iversen},
  journal={Acta physiologica Scandinavica},
  volume={169 3},
The field of calcium signalling has evolved rapidly the last 20 years. Physiologists had worked with cytosolic Ca2+ as the coupler of excitation and contraction of muscles and as a secretory signal in exocrine glands and in the synapses of the brain for several decades before the discovery of cellular calcium as a second messenger. Development of powerful techniques for measuring the concentration of cytosolic free calcium ions in cell suspensions and later in single cells and even in different… CONTINUE READING

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