Rule-based multi-level modeling of cell biological systems

  title={Rule-based multi-level modeling of cell biological systems},
  author={Carsten Maus and Stefan Rybacki and Adelinde M. Uhrmacher},
  booktitle={BMC Systems Biology},
Proteins, individual cells, and cell populations denote different levels of an organizational hierarchy, each of which with its own dynamics. Multi-level modeling is concerned with describing a system at these different levels and relating their dynamics. Rule-based modeling has increasingly attracted attention due to enabling a concise and compact description of biochemical systems. In addition, it allows different methods for model analysis, since more than one semantics can be defined for… CONTINUE READING
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