Ruggedness and robustness testing.

  title={Ruggedness and robustness testing.},
  author={Bieke Dejaegher and Yvan Vander Heyden},
  journal={Journal of chromatography. A},
  volume={1158 1-2},
Due to the strict regulatory requirements, especially in pharmaceutical analysis, analysis results with an acceptable quality should be reported. Thus, a proper validation of the measurement method is required. In this context, ruggedness and robustness testing becomes increasingly more important. In this review, the definitions of ruggedness and robustness are given, followed by a short explanation of the different approaches applied to examine the ruggedness or the robustness of an analytical… CONTINUE READING