Rubisco: structure, regulatory interactions, and possibilities for a better enzyme.

  title={Rubisco: structure, regulatory interactions, and possibilities for a better enzyme.},
  author={Robert J. Spreitzer and Michael E. Salvucci},
  journal={Annual review of plant biology},
Ribulose-1,5-bisphosphate (RuBP) carboxylase/oxygenase (Rubisco) catalyzes the first step in net photosynthetic CO2 assimilation and photorespiratory carbon oxidation. The enzyme is notoriously inefficient as a catalyst for the carboxylation of RuBP and is subject to competitive inhibition by O2, inactivation by loss of carbamylation, and dead-end inhibition by RuBP. These inadequacies make Rubisco rate limiting for photosynthesis and an obvious target for increasing agricultural productivity… 

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Catalysis and regulation in Rubisco.

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