• Corpus ID: 150385664

Rubinstein : enduring contributions to neuro-oncology

@inproceedings{Mut2005RubinsteinE,
  title={Rubinstein : enduring contributions to neuro-oncology},
  author={Melike Mut and M. and Beatr{\'i}z and {\vS}. and Lopes and Mark E. Shaffrey},
  year={2005}
}
Lucien Rubinstein was born in Antwerp, Belgium on October 15, 1924, but immigrated to England during the Second World War. After a year at Queen Mary College, he was admitted to the Medical College of London Hospital, from which he graduated as an M.D. in 1952. After his military service, he joined the staff of the Bernhard Baron Institute of Pathology at the Royal London Hospital and collaborated with Professor Dorothy Russell. After a sabbatical year in which his time was split between the… 
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References

SHOWING 1-10 OF 102 REFERENCES
The Art of Brain Tumour Classification ‐A Tribute to Lucien J. Rubinstein (1925–1990)
On the occasion of a WHO Meeting on Brain Tumour Classification which was held in Zurich during March 29–31, several friends and colleagues shared their memories of Dr Lucien J. Rubinstein who died
Histopathological features of recurrent pleomorphic xanthoastrocytomas: further corroboration of the glial nature of this neoplasm
TLDR
Three further examples of locally recurrent neoplasms in patients whose original meningocerebral tumors had the typical features of PXA are reported; the recurrences were small-cell glioblastomas, which further confirms the astrocytic nature of the PxA.
The pathways of extraneural spread in metastasizing gliomas: a report of three cases and critical review of the literature.
TLDR
It is clear that transdural access in continuity is not necessarily provided through the operative flap and that it may occur at sites removed from, or independent of, the site of operation, as demonstrated in two of the three cases described in this article.
Lack of histopathological correlation of malignant ependymomas with postoperative survival.
TLDR
An attempt was made to correlate 15 cases of histologically malignant ependymoma with clinical recurrence and postoperative patient survival times, and no correlation was possible between the tumor's histological features, site, or likelihood of recurrence.
Astroblastomas: a pathological study of 23 tumors, with a postoperative follow-up in 13 patients.
TLDR
This form of glioma illustrates the discrepancies that may sometimes be apparent between histopathological features and length of postoperative survival and the prognosis is also further complicated by the potential of the astroblastoma to convert into a more malignant type ofglioma.
Ependymoblastoma. A reappraisal of a rare embryonal tumor
TLDR
The absence of pleomorphism, giant cells, multinucleation and pseudopalisades, and the scanty proliferation of vascular endothelial cells are additional features that delineate this tumor from an anaplastic (malignant) ependymoma.
The application of glial fibrillary acidic (GFA) protein immunohistochemistry in neurooncology. A progress report.
TLDR
The present review is to summarize the principal conclusions to date, to examine the implications inherent in some of the findings and to address ourselves to a number of pertinent questions which the application of this technique is currently raising.
The biological behavior of primary cerebral neuroblastoma: A reappraisal of the clincal course in a series of 70 cases
TLDR
Patients with a tumors of the desmoplastic or transitional variant without ganglionic differentiation had a lower mean age at the time of diagnosis than those harboring a tumor of the classic variant, and age could not be correlated with the presence of ganglionics.
Subependymal giant cell astrocytoma. Significance and possible cytogenetic implications of an immunohistochemical study.
TLDR
This study suggests that the SGCA, especially those associated with tuberous sclerosis, include cells that are apparently unable to express GFA protein, which falls short of the complete expression of neuronal differentiation.
Neural differentiation in the OTT-6050 mouse teratoma
TLDR
The absence of non-neural cells in the IB-21 tumor fraction and its ability to demonstrate divergent neural differentiation suggest that a transplantable neural-determined cell population exists in the OTT-6050 mouse teratoma.
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