Rubidium chloride ingestion by volunteer subjects: Initial experience

@article{Fieve2004RubidiumCI,
  title={Rubidium chloride ingestion by volunteer subjects: Initial experience},
  author={Ronald R. Fieve and Herbert L. Meltzer and Reginald Morton Taylor},
  journal={Psychopharmacologia},
  year={2004},
  volume={20},
  pages={307-314}
}
The authors report on the first metabolically controlled study of rubidium chloride administered to humans. Four subjects were given doses of 8.2–12.4 meq. RbCl in a single day, and biological half lives calculated from urinary excretion ranged from 21–55 days. A long term study of chronic rubidium loading in one of these subjects demonstrated no undesirable clinical side effects. After ingestion of a total dose of 268 meq. within a period of 75 days a plasma level of 0.16 meq./liter rubidium… 

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