Rs56288038 (C/G) in 3'UTR of IRF-1 Regulated by MiR-502-5p Promotes Gastric Cancer Development.

@article{Wang2016Rs56288038I,
  title={Rs56288038 (C/G) in 3'UTR of IRF-1 Regulated by MiR-502-5p Promotes Gastric Cancer Development.},
  author={Bo Wang and Huan Yang and Liqin Shen and Ji Wang and Wangyang Pu and Zhigang Chen and Xudong Shen and Jinxiang Fu and Zhixiang Zhuang},
  journal={Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology},
  year={2016},
  volume={40 1-2},
  pages={
          391-399
        }
}
BACKGROUND/AIMS Interferon regulatory factor 1 (IRF-1) has been shown to function as a transcriptional activator or repressor of a variety of target genes. However, its upstream, non-coding RNA-related regulatory capacity remains unknown. In this study, we focus on the miRNA-associated single nucleotide polymorphisms (SNPs) in the 3'untranslated region (UTR) of IRF-1 to further investigate the functional relationship and potential diagnostic value of the SNPs and miRNAs among Chinese gastric… CONTINUE READING

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