RpoS-Mediated Growth-Dependent Expression of the Escherichia coli tkt Genes Encoding Transketolases Isoenzymes

@article{Jung2005RpoSMediatedGE,
  title={RpoS-Mediated Growth-Dependent Expression of the Escherichia coli tkt Genes Encoding Transketolases Isoenzymes},
  author={Il Lae Jung and Ki Heon Phyo and In-Gyu Kim},
  journal={Current Microbiology},
  year={2005},
  volume={50},
  pages={314-318}
}
Escherichia coli tktA and tktB genes encode two transketolase isoenzymes involved in the pentose-phosphate pathway, In this study, two reporter lacZ fusions, tktA- and tktB-lacZ, were constructed to examine their transcriptional regulation on the E. coli chromosome. The tktA gene was induced in the exponential growth phase and suppressed in the stationary growth phase. However, the genetic elimination of the rpoS, whose product is an alternative sigma factor (RpoS), derepressed the tktA gene… CONTINUE READING