Royal jelly protects against ultraviolet B-induced photoaging in human skin fibroblasts via enhancing collagen production.

@article{Park2011RoyalJP,
  title={Royal jelly protects against ultraviolet B-induced photoaging in human skin fibroblasts via enhancing collagen production.},
  author={Hye Min Park and Eunson Hwang and Kwang-gill Lee and Sang Mi Han and Yunhi Cho and Sun Yeou Kim},
  journal={Journal of medicinal food},
  year={2011},
  volume={14 9},
  pages={
          899-906
        }
}
Royal jelly (RJ) is a honeybee product containing proteins, carbohydrates, fats, free amino acids, vitamins, and minerals. As its principal unsaturated fatty acid, RJ contains 10-hydroxy-2-decenoic acid (10-HDA), which may have antitumor and antibacterial activity and a capacity to stimulate collagen production. RJ has attracted interest in various parts of the world for its pharmacological properties. However, the effects of RJ on ultraviolet (UV)-induced photoaging of the skin have not been… 
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63 Citations
Background Citations
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Methods Citations
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Results Citations
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63 Citations

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A Comparative Study of Baby Immature and Adult Shoots of Aloe Vera on UVB‐Induced Skin Photoaging in vitro

The results suggest that BAE may potentially protect the skin from UVB‐induced damage more than AE, and type I procollagen and TGF‐β1 levels after UVB irradiation.

Bee-derived antibacterial peptide, defensin-1, promotes wound re-epithelialisation in vitro and in vivo

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26 References

Identification of a Collagen Production-promoting Factor from an Extract of Royal Jelly and Its Possible Mechanism

HBRJ-CPF identified as 10H2DA promoted the collagen production of AA-2G-treated fibroblasts by inducing TGF-β1 production, which is an important factor for collagen production.

Possible involvement of gelatinases in basement membrane damage and wrinkle formation in chronically ultraviolet B-exposed hairless mouse.

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10-Hydroxy-2-decenoic Acid, a Major Fatty Acid from Royal Jelly, Inhibits VEGF-induced Angiogenesis in Human Umbilical Vein Endothelial Cells

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Royal jelly possesses an anti-inflammatory action and is able to augment wound healing, but does not have an insulin-like action in streptozotocin-diabetic rats.

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The results suggest that POMx protects HaCaT cells against UVB‐induced oxidative stress and markers of photoaging and could be a useful supplement in skin care products.