Routing MAP Kinase Cascades

@article{Elion1998RoutingMK,
  title={Routing MAP Kinase Cascades},
  author={Elaine A. Elion},
  journal={Science},
  year={1998},
  volume={281},
  pages={1625 - 1626}
}
  • E. Elion
  • Published 11 September 1998
  • Biology
  • Science
Cells need to convey information from signals on their surface to a variety of intracellular targets, including transcription factors, contractile proteins, and enzymes. To do so efficiently, they construct information pathways with enzymes called kinases, using the same enzymes over and over. But what prevents cross talk between pathways? In her Perspective, Elion discusses new results in this issue by Whitmarsh et al. and Schaeffer et al., who identify proteins that act as scaffolds in… 
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