Routine use of corticosteroids to prevent inflammation response in cardiac surgery.

@article{Nebelsiek2012RoutineUO,
  title={Routine use of corticosteroids to prevent inflammation response in cardiac surgery.},
  author={Tim Nebelsiek and Andr{\'e}s Beiras-Fern{\'a}ndez and Erich Kilger and Patrick Moehnle and Florian C. Weis},
  journal={Recent patents on cardiovascular drug discovery},
  year={2012},
  volume={7 3},
  pages={170-4}
}
Cardiac surgery, especially if it involves cardiopulmonary bypass, is associated with a severe systemic inflammatory response. It is characterized by complement activation and initiation of coagulation, fibrinolysis and kallikrein cascades. Consecutive activation of immunoregulatory cells results in an extensive release of pro- and anti-inflammatory… CONTINUE READING