Routine screening for sickle cell haemoglobinopathy by electrophoresis in an infant welfare clinic.

@article{Omotade1998RoutineSF,
  title={Routine screening for sickle cell haemoglobinopathy by electrophoresis in an infant welfare clinic.},
  author={Olayemi O. Omotade and C M Kayode and S L Falade and Samuel Ikpeme and Adebolajo A Adeyemo and F M Akinkugbe},
  journal={West African journal of medicine},
  year={1998},
  volume={17 2},
  pages={91-4}
}
The experience of a Nigerian infant welfare clinic in offering sickle cell haemoglo-binopathy (SCH) screening by electrophoresis to its clinic population over a 12-year period is reported. Overall 10,115 children were screened. Homozygous haemoglobin S was detected in 3.1% and haemoglobin S + C in 1.1%. Carriers of the sickle cell gene (haemoglobin A + S) comprised 23.7% of the children screened. Gene frequencies for the A, S and C genes were 0.814, 0.155 and 0.031 respectively. The gene… CONTINUE READING

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