Routine hospital use of a new commercial whole blood interferon-gamma assay for the diagnosis of tuberculosis infection.

@article{Ferrara2005RoutineHU,
  title={Routine hospital use of a new commercial whole blood interferon-gamma assay for the diagnosis of tuberculosis infection.},
  author={Giovanni Ferrara and Monica Losi and Marisa Meacci and Barbara Meccugni and Roberto Piro and Pietro Roversi and Barbara Maria Bergamini and R D'amico and Patrizia Marchegiano and Fabio Rumpianesi and Leonardo M Fabbri and Luca Richeldi},
  journal={American journal of respiratory and critical care medicine},
  year={2005},
  volume={172 5},
  pages={631-5}
}
RATIONALE Interferon (IFN)-gamma blood tests may improve the current level of diagnostic accuracy for tuberculosis infection. The QuantiFERON-TB Gold (QFT-Gold) has been used in selected populations and shows higher specificity than the tuberculin skin test (TST). OBJECTIVE To evaluate the QFT-Gold test in unselected patients and assess the level of agreement with the TST. METHODS The test has been routinely performed on whole blood samples in our microbiology laboratory for 8 months… CONTINUE READING