Rous sarcoma virus-transformed cells develop peculiar adhesive structures along the cell periphery.

@article{Nakamura1993RousSV,
  title={Rous sarcoma virus-transformed cells develop peculiar adhesive structures along the cell periphery.},
  author={Naoya Nakamura and Junya Tanaka and Kenji Sobue},
  journal={Journal of cell science},
  year={1993},
  volume={106 ( Pt 4)},
  pages={1057-69}
}
Alteration of the cell/substratum adhesive structures of rat fibroblasts (3Y1 cells) upon transformation by Rous sarcoma virus (RSV) was investigated by immunofluorescence microscopy. In serum-containing culture medium, 3Y1 cells developed focal adhesions as their main adhesive structures, while BY1 cells expressed peculiar close contacts along the cell periphery with the vitronectin receptor integrin, in addition to podosomes. These peripheral close contacts are referred to as the peripheral… CONTINUE READING

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