Rough Deal and Zw10 are required for the metaphase checkpoint in Drosophila

@article{Basto2000RoughDA,
  title={Rough Deal and Zw10 are required for the metaphase checkpoint in Drosophila},
  author={Renata Basto and Rui Fonseca dos Santos Gomes and Roger E. Karess},
  journal={Nature Cell Biology},
  year={2000},
  volume={2},
  pages={939-943}
}
The metaphase–anaphase transition during mitosis is carefully regulated in order to assure high-fidelity transmission of genetic information to the daughter cells. A surveillance mechanism known as the metaphase checkpoint (or spindle-assembly checkpoint) monitors the attachment of kinetochores to the spindle microtubules, and inhibits anaphase onset until… CONTINUE READING