Rottlerin and Cancer: Novel Evidence and Mechanisms

  title={Rottlerin and Cancer: Novel Evidence and Mechanisms},
  author={Emanuela Maioli and Claudia Torricelli and Giuseppe Valacchi},
Because cancers are caused by deregulation of hundreds of genes, an ideal anticancer agent should target multiple gene products or signaling pathways simultaneously. Recently, extensive research has addressed the chemotherapeutic potential of plant-derived compounds. Among the ever-increasing list of naturally occurring anticancer agents, Rottlerin appears to have great potentiality for being used in chemotherapy because it affects several cell machineries involved in survival, apoptosis… CONTINUE READING
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