Rotigotine, a dopamine receptor agonist, increased BDNF protein levels in the rat cortex and hippocampus

@article{Adachi2018RotigotineAD,
  title={Rotigotine, a dopamine receptor agonist, increased BDNF protein levels in the rat cortex and hippocampus},
  author={Naoki Adachi and Aya Yoshimura and Shuichi Chiba and Shintaro Ogawa and Hiroshi Kunugi},
  journal={Neuroscience Letters},
  year={2018},
  volume={662},
  pages={44-50}
}
Brain-derived neurotrophic factor (BDNF) critically controls the fate and function of the neuronal network and has received much attention as a target of many brain diseases. Dopaminergic system dysfunction has also been implicated in a variety of neuropsychiatric diseases. Rotigotine, a non-ergot dopamine receptor agonist, is used in the treatment of Parkinson's disease and restless legs syndrome. To investigate the effects of rotigotine on neuronal functions both in vivo and in vitro, rats… CONTINUE READING

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