Rotavirus vaccines: targeting the developing world.

  title={Rotavirus vaccines: targeting the developing world.},
  author={Roger I. Glass and Joseph S. Bresee and Reina M Turcios and Thea K\olsen Fischer and Umesh Parashar and A. Duncan Steele},
  journal={The Journal of infectious diseases},
  volume={192 Suppl 1},
For the past 2 decades, rotavirus infection, the most common cause of severe diarrhea in children, has been a priority target for vaccine development. This decision to develop rotavirus vaccines is predicated on the great burden associated with fatal rotavirus disease (i.e., 440,000 deaths/year), the firm scientific basis for developing live oral vaccines, the belief that increased investment in development at this time could speed the introduction of vaccines in developing countries, and the… CONTINUE READING