Rotavirus infection of MA104 cells is inhibited by Ricinus lectin and separately expressed single binding domains.

Abstract

Various lectins were tested for blocking rotavirus infection of MA104 cells and it was observed that galactose-specific lectins were the most inhibitory. Of these Ricinus agglutinin was able to inhibit infection (by human and animal strains) at concentrations as low as 10(-9) M. In addition, in a virus overlay protein blot assay Ricinus agglutinin competed… (More)

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@article{Jolly2000RotavirusIO, title={Rotavirus infection of MA104 cells is inhibited by Ricinus lectin and separately expressed single binding domains.}, author={Cath Jolly and B. M. Beisner and Ian H. Holmes}, journal={Virology}, year={2000}, volume={275 1}, pages={89-97} }