Rotavirus genotyping: keeping up with an evolving population of human rotaviruses.

@article{IturrizaGmara2004RotavirusGK,
  title={Rotavirus genotyping: keeping up with an evolving population of human rotaviruses.},
  author={Miren Iturriza-G{\'o}mara and Gagandeep Kang and J. Alan Gray},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  year={2004},
  volume={31 4},
  pages={259-65}
}
The use of molecular methods for rotavirus characterisation provides not only increased sensitivity for typing, but also allows accurate and more complete characterisation of strains, and the identification of putative reassortant strains. However, due to the constant accumulation of point mutations through genetic drift, and to the emergence of novel genotypes, possibly zoonotic transmission and subsequent reassortment, the reagents and methods used require close monitoring and updating… CONTINUE READING
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