Rotavirus Overview

@article{Bernstein2009RotavirusO,
  title={Rotavirus Overview},
  author={David I Bernstein},
  journal={The Pediatric Infectious Disease Journal},
  year={2009},
  volume={28},
  pages={S50-S53}
}
  • D. Bernstein
  • Published 1 March 2009
  • Medicine
  • The Pediatric Infectious Disease Journal
Rotaviral gastroenteritis is a serious public health problem in both developed and developing countries. The disease is ubiquitous, affecting nearly all children by the age of 5 years. It is the most common cause of hospitalizations for gastroenteritis among children in the United States (30%–70% depending on the season) and is associated with direct and indirect costs of approximately $1 billion per year. Symptoms of rotaviral gastroenteritis are nonspecific (ie, diarrhea, vomiting, and fever… 
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References

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TLDR
RV detection was greatest when diarrhea, vomiting and fever occurred together and lowest when each symptom occurred alone, suggesting the spectrum of symptoms of rotavirus disease in children at the time of admission to the hospital or short stay unit may be broader than previously recognized.
Rotavirus infection in adults
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TLDR
The largest US hospital discharge database available, the Healthcare Cost and Utilization Project (HCUP), is used to study national rates, trends, and risk factors for diarrhea- and rotavirus-associated hospitalizations and deaths among children <5 years of age, to establish a baseline against which vaccine implementation can be measured.
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TLDR
The results from the largest prospective study in the United States determining the nonmedical costs of severe rotavirus infections may exceed $22 million annually are reported, suggesting that the non medical costs associated with mild to moderate rotav virus disease have been similarly underestimated.
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TLDR
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Rotavirus vaccines: current prospects and future challenges
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TLDR
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TLDR
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TLDR
The sensitivity of the rotavirus ICD code among children hospitalized for AGE by using active surveillance forRotavirus at a tertiary children's hospital was evaluated and it was indicated that the numbers of national rotav virus hospitalization discharges may be substantially greater than previously estimated.
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