Rotational dynamics of calcium-free calmodulin studied by 15N-NMR relaxation measurements.

@article{Tjandra1995RotationalDO,
  title={Rotational dynamics of calcium-free calmodulin studied by 15N-NMR relaxation measurements.},
  author={Nico Tjandra and Hitoshi Kuboniwa and H. C. Ren and Adriaan Bax},
  journal={European journal of biochemistry},
  year={1995},
  volume={230 3},
  pages={1014-24}
}
The backbone motions of calcium-free Xenopus calmodulin have been characterized by measurements of the 15N longitudinal relaxation times (T1) at 51 and 61 MHz, and by conducting transverse relaxation (T2), spin-locked transverse relaxation (T1 rho), and 15N-[1H] heteronuclear NOE measurements at 61 MHz 15N frequency. Although backbone amide hydrogen exchange experiments indicate that the N-terminal domain is more stable than calmodulin's C-terminal half, slowly exchanging backbone amide protons… CONTINUE READING

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