Rosuvastatin in experimental brain trauma: improved capillary patency but no effect on edema or cerebral blood flow.

@article{Jungner2013RosuvastatinIE,
  title={Rosuvastatin in experimental brain trauma: improved capillary patency but no effect on edema or cerebral blood flow.},
  author={M{\aa}rten Jungner and Cornelia Lundblad and Peter Bentzer},
  journal={Microvascular research},
  year={2013},
  volume={88},
  pages={
          48-55
        }
}
BACKGROUND Microvascular dysfunction, characterized by edema formation secondary to increased blood-brain barrier (BBB) permeability and decreased blood flow, contributes to poor outcome following brain trauma. Recent studies have indicated that statins may counteract edema formation following brain trauma but little is known about other circulatory effects of statins in this setting. The objective of this study was to investigate whether statin treatment improves brain microcirculation early… CONTINUE READING

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