Rostral anterior cingulate cortex activity and early symptom improvement during treatment for major depressive disorder.


In treatment trials for major depressive disorder (MDD), early symptom improvement is predictive of eventual clinical response. Clinical response may also be predicted by elevated pretreatment theta (4-7Hz) current density in the rostral anterior cingulate (rACC) and medial orbitofrontal cortex (mOFC). We investigated the relationship between pretreatment… (More)
DOI: 10.1016/j.pscychresns.2010.12.007