Ross River virus glycoprotein-pseudotyped retroviruses and stable cell lines for their production.

@article{Sharkey2001RossRV,
  title={Ross River virus glycoprotein-pseudotyped retroviruses and stable cell lines for their production.},
  author={C Matthew Sharkey and Christopher North and Richard J. Kuhn and David Avram Sanders},
  journal={Journal of virology},
  year={2001},
  volume={75 6},
  pages={2653-9}
}
Pseudotyped retroviruses have important applications as vectors for gene transfer and gene therapy and as tools for the study of viral glycoprotein function. Recombinant Moloney murine leukemia virus (Mo-MuLV)-based retrovirus particles efficiently incorporate the glycoproteins of the alphavirus Ross River virus (RRV) and utilize them for entry into cells. Stable cell lines that produce the RRV glycoprotein-pseudotyped retroviruses for prolonged periods of time have been constructed. The… CONTINUE READING
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