Rosmarinic acid stimulates liver regeneration through the mTOR pathway.

  title={Rosmarinic acid stimulates liver regeneration through the mTOR pathway.},
  author={Kaihan Lou and Min Yang and Erdan Duan and Jiahui Zhao and Cong Yu and Rongping Zhang and Lanchun Zhang and Ming Zhang and Zhicheng Xiao and Weiyan Hu and Zhiyong He},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  volume={23 13},
BACKGROUND Rosemary (Rosmarinus offcinsalis L) has a liver protection function under various conditions of liver damage. Rosmarinic acid, one of the pharmacological constituents of rosemary, exhibited protective effects against organ injury, including acute liver injury. HYPOTHESIS We hypothesize that RA stimulates liver regeneration. STUDY DESIGN In the present study, we investigated the effects and mechanism of RA administration on liver regeneration using partial hepatectomy (PH), a well… CONTINUE READING


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