Rosmarinic acid production by Coleus forskohliihairy root cultures

  title={Rosmarinic acid production by Coleus forskohliihairy root cultures},
  author={Wei Li and Kazuo Koike and Yoshihisa Asada and Takafumi Yoshikawa and Tamotsu Nikaido},
  journal={Plant Cell, Tissue and Organ Culture},
Coleus forskohlii hairy root cultures were found to produce forskolin and rosmarinic acid (RA) as the main metabolites. The growth and RA production by C. forskohlii hairy root cultures in various liquid media were examined. The hairy root cultures showed good growth in hormone-free Murashige and Skoog medium containing 3% (w/v) sucrose (MS medium), and Gamborg B5 medium containing 2% (w/v) sucrose (B5 medium). RA yield reached 4.0 mg (MS medium) and 4.4 mg (B5 medium) after 5 weeks of culture… CONTINUE READING
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