Rosmarinic acid induces melanogenesis through protein kinase A activation signaling.

@article{Lee2007RosmarinicAI,
  title={Rosmarinic acid induces melanogenesis through protein kinase A activation signaling.},
  author={Jongsung Lee and Yeong Shik Kim and Deokhoon Park},
  journal={Biochemical pharmacology},
  year={2007},
  volume={74 7},
  pages={960-8}
}
Melanogenesis is a physiological process that results in the synthesis of melanin pigments, which play a crucial protective role against skin photocarcinogenesis. In order to determine the effects of rosmarinic acid on melanogenesis and elucidate the molecular events of melanogenesis induced by rosmarinic acid, several experiments were performed in B16 melanoma cells. In this study, we showed that the melanin content and tyrosinase expression were increased by rosmarinic acid in a concentration… CONTINUE READING
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