Rosmarinic Acid as a Novel Agent in the Treatment of Autoimmune Disease

  title={Rosmarinic Acid as a Novel Agent in the Treatment of Autoimmune Disease},
  author={Jill Stansbury and Paul Richard Saunders and David Winston and Eugene R. Zampieron},
Rosmarinic acid has been shown to selectively induce T cell apoptosis in aberrant lymphocytes, but not normal/quiescent T cells. Rosmarinic acid also reduces gamma interferon driven T cell responses and reduces interleukin production following T cell stimulation. Furthermore, rosmarinic acid affects signal transduction inside T cells by affecting specific tyrosine kinase enzymes inside the cell. By direct effects on T cells as well as other anti-inflammatory and antioxidant effects, rosmarinic… Expand

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