Rosiglitazone reverses salbutamol-induced β(2) -adrenoceptor tolerance in airway smooth muscle.

Abstract

BACKGROUND AND PURPOSE β₂-Adrenoceptor agonists are important therapeutic agents in the treatment of asthma and chronic obstructive pulmonary disease. The regular use of these drugs has been associated with proasthmatic-like changes that limit their efficacy and increase the risk of severe adverse reactions. We investigated whether the peroxisome… (More)
DOI: 10.1111/j.1476-5381.2010.01021.x

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Cite this paper

@article{Fogli2011RosiglitazoneRS, title={Rosiglitazone reverses salbutamol-induced β(2) -adrenoceptor tolerance in airway smooth muscle.}, author={Stefano Fogli and Silvia Pellegrini and Barbara Adinolfi and Veronica Mariotti and Erika Melissari and Laura Betti and Laura Fabbrini and Gino Giannaccini and Antonio Lucacchini and Claudio Bardelli and Fabio Stefanelli and Sandra Brunelleschi and Maria Cristina Breschi}, journal={British journal of pharmacology}, year={2011}, volume={162 2}, pages={378-91} }