Rosai-Dorfman-type histiocytes occur in eosinophilic chronic rhinosinusitis and potentially play a role in disease initiation and persistence.

@article{Wilsher2016RosaiDorfmantypeHO,
  title={Rosai-Dorfman-type histiocytes occur in eosinophilic chronic rhinosinusitis and potentially play a role in disease initiation and persistence.},
  author={Mark James Wilsher and Fiona Bonar},
  journal={Histopathology},
  year={2016},
  volume={69 4},
  pages={655-66}
}
AIMS We recently identified the presence of Rosai-Dorfman-type histiocytes (RDH) in sinonasal tissue removed from individuals with eosinophilic chronic rhinosinusitis (ECR). We sought to determine their clinical significance. METHODS AND RESULTS Sinonasal biopsies from 10 individuals (index cases) with classical features of ECR and the additional finding of RDH were collected during a two-and-a-half-year period. Twenty-one sinonasal biopsies with a diagnosis of ECR accrued during a 6-month… CONTINUE READING
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