Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma

@inproceedings{Wright2009Ror2AD,
  title={Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma},
  author={Tricia M. Wright and Angela Rose Brannon and John D Gordan and Amanda J Mikels and Cicely E Mitchell and Shufen Chen and Inigo Espinosa and Matt van de Rijn and Raj Som Pruthi and Eric. M. Wallen and Lloyd J. Edwards and Roeland Nusse and W. Kimryn Rathmell},
  booktitle={Oncogene},
  year={2009}
}
Inappropriate kinase expression and subsequent promiscuous activity defines the transformation of many solid tumors including renal cell carcinoma (RCC). Thus, the expression of novel tumor-associated kinases has the potential to dramatically shape tumor cell behavior. Further, identifying tumor-associated kinases can lend insight into patterns of tumor growth and characteristics. Here, we report the identification of the RTK-like orphan receptor 2 (Ror2), a new tumor-associated kinase in RCC… CONTINUE READING
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