Ror receptor tyrosine kinases: orphans no more.

@article{Green2008RorRT,
  title={Ror receptor tyrosine kinases: orphans no more.},
  author={Jennifer L. Green and Steven G. Kuntz and Paul W. Sternberg},
  journal={Trends in cell biology},
  year={2008},
  volume={18 11},
  pages={536-44}
}
Receptor tyrosine kinase-like orphan receptor (Ror) proteins are a conserved family of tyrosine kinase receptors that function in developmental processes including skeletal and neuronal development, cell movement and cell polarity. Although Ror proteins were originally named because the associated ligand and signaling pathway were unknown, recent studies in multiple species have now established that Ror proteins are Wnt receptors. Depending on the cellular context, Ror proteins can either… CONTINUE READING
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Themutation ROR2W749X, linked to human BDB, is a recessivemutation in themouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome

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