Ropinirole is effective in the long-term management of restless legs syndrome: a randomized controlled trial.

@article{Montplaisir2006RopiniroleIE,
  title={Ropinirole is effective in the long-term management of restless legs syndrome: a randomized controlled trial.},
  author={Jacques Y. Montplaisir and Jeff Karrasch and Jean Haan and Dieter Volc},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2006},
  volume={21 10},
  pages={1627-35}
}
The objective of this study was to investigate the long-term efficacy of ropinirole in patients with restless legs syndrome (RLS) and to assess the potential for relapse after the discontinuation of active treatment. Patients with primary RLS (n = 202) received single-blind ropinirole for 24 weeks. Patients meeting treatment continuation criteria were randomized to double-blind treatment with ropinirole or placebo for a further 12 weeks. The primary efficacy variable was the proportion of… CONTINUE READING

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Treatment of restless legs syndrome: an evidence-based review and implications for clinical practice.

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