Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase gene duplications.

@article{Brown1995RootOT,
  title={Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase gene duplications.},
  author={Jean Brown and W. Ford Doolittle},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 7},
  pages={2441-5}
}
Universal trees based on sequences of single gene homologs cannot be rooted. Iwabe et al. [Iwabe, N., Kuma, K.-I., Hasegawa, M., Osawa, S. & Miyata, T. (1989) Proc. Natl. Acad. Sci. USA 86, 9355-9359] circumvented this problem by using ancient gene duplications that predated the last common ancestor of all living things. Their separate, reciprocally rooted gene trees for elongation factors and ATPase subunits showed Bacteria (eubacteria) as branching first from the universal tree with Archaea… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 130 extracted citations

Similar Papers

Loading similar papers…