Root and Eruption Defects in c-Fos Mice Are Driven by Loss of Osteoclasts.

Abstract

c-Fos homozygous mice lack osteoclasts with a failure of the teeth to erupt and with an arrest of root development. Here, we characterize the defects associated with the failure in root development and the loss of the tooth-bone interface, and we investigate the underlying causes. We show that, while homozygous c-Fos mice have no multinucleated osteoclasts… (More)
DOI: 10.1177/0022034515608828

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Cite this paper

@article{Alfaqeeh2015RootAE, title={Root and Eruption Defects in c-Fos Mice Are Driven by Loss of Osteoclasts.}, author={Sarah A Alfaqeeh and Veronika Oralov{\'a} and M Foxworthy and Eva Matalov{\'a} and Agamemnon E. Grigoriadis and Abigail S Tucker}, journal={Journal of dental research}, year={2015}, volume={94 12}, pages={1724-31} }