Room temperature palladium-catalyzed cross coupling of aryltrimethylammonium triflates with aryl Grignard reagents.

@article{Reeves2010RoomTP,
  title={Room temperature palladium-catalyzed cross coupling of aryltrimethylammonium triflates with aryl Grignard reagents.},
  author={J. T. Reeves and Daniel R Fandrick and Z. Tan and J. Song and Heewon Lee and N. Yee and C. Senanayake},
  journal={Organic letters},
  year={2010},
  volume={12 19},
  pages={
          4388-91
        }
}
Aryltrimethylammonium triflates and tetrafluoroborates were found to be highly reactive electrophiles in the Pd-catalyzed cross coupling with aryl Grignard reagents. The coupling reactions proceed at ambient temperature with a nearly stoichiometric quantity of Grignard reagent, and diverse functionality is tolerated. Competition experiments established the reactivity of PhNMe(3)OTf relative to PhCl, PhBr, PhI, and PhOTf. 
88 Citations
Nickel-catalyzed cross-coupling of aryltrimethylammonium triflates and amines.
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