Room-temperature macromolecular serial crystallography using synchrotron radiation

@inproceedings{Stellato2014RoomtemperatureMS,
  title={Room-temperature macromolecular serial crystallography using synchrotron radiation},
  author={Francesco Stellato and Dominik Oberthuer and Mengning Liang and Richard Bean and Cornelius Gati and Oleksandr Yefanov and Anton Barty and Anja Burkhardt and Pontus Fischer and Lorenzo Galli and Richard A. Kirian and Jan Meyer and Saravanan Panneerselvam and Chun Hong Yoon and Fedor Chervinskii and Emily M. Speller and Thomas A. White and Christian Betzel and Alke Meents and Henry N. Chapman},
  booktitle={IUCrJ},
  year={2014}
}
A new approach for collecting data from many hundreds of thousands of microcrystals using X-ray pulses from a free-electron laser has recently been developed. Referred to as serial crystallography, diffraction patterns are recorded at a constant rate as a suspension of protein crystals flows across the path of an X-ray beam. Events that by chance contain single-crystal diffraction patterns are retained, then indexed and merged to form a three-dimensional set of reflection intensities for… CONTINUE READING

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