Room for more IL-6 blockade? Sarilumab for the treatment of rheumatoid arthritis.

Abstract

INTRODUCTION Rheumatoid arthritis (RA) treatment has been revolutionized by the development of highly efficacious biotherapeutics. However, a significant subset of RA patients has persistently active disease and ongoing erosive joint damage despite the available therapies. Sarilumab targets interleukin-6, one of the main cytokines mediating inflammation in… (More)
DOI: 10.1080/14712598.2016.1217988

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