Roles of tyrosine kinase and protein kinase C in infarct size limitation by repetitive ischemic preconditioning in the rat.

@article{Tanno2000RolesOT,
  title={Roles of tyrosine kinase and protein kinase C in infarct size limitation by repetitive ischemic preconditioning in the rat.},
  author={Masaya Tanno and Akihito Tsuchida and Yukinaga Nozawa and Tetsuya Matsumoto and Tohru Hasegawa and Tetsuji Miura and Kazuaki Shimamoto},
  journal={Journal of cardiovascular pharmacology},
  year={2000},
  volume={35 3},
  pages={345-52}
}
In this study, we examined the possibility that infarct-size limitation by repetitive preconditioning (PC) is achieved by activation of both protein kinase C (PKC) and tyrosine kinase. In addition, we assessed whether such kinase activation is triggered by angiotensin II type 1 (AT1) and alpha1-adrenergic receptors and whether sarcolemmal and mitochondrial adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channels play roles as effectors of cardioprotection in the rat. Under… CONTINUE READING
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