Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division

  title={Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division},
  author={Becket Feierbach and Fred Chang},
  journal={Current Biology},
BACKGROUND Both symmetric and asymmetric cell divisions are required for the generation of appropriate cell lineages during development. Wild-type Schizosaccharomyces pombe cells divide in a symmetric fashion to produce two similar rod-shaped daughter cells. Formins are proteins with conserved roles in cell polarity, cytokinesis, and the regulation of actin and microtubule cytoskeletons. RESULTS Here, we identify and characterize a new S. pombe formin, for3p. for3 Delta mutant cells divide in… CONTINUE READING
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