Roles of the cytoplasmic and transmembrane domains of syntaxins in intracellular localization and trafficking.

@article{Kasai2001RolesOT,
  title={Roles of the cytoplasmic and transmembrane domains of syntaxins in intracellular localization and trafficking.},
  author={Ken-ichi Kasai and Kimio Akagawa},
  journal={Journal of cell science},
  year={2001},
  volume={114 Pt 17},
  pages={3115-24}
}
Syntaxins are target-soluble N-ethylmaleimide-sensitive factor-attachment protein receptors (t-SNAREs) involved in docking and fusion of vesicles in exocytosis and endocytosis. Many syntaxin isoforms have been isolated, and each one displays a distinct intracellular localization pattern. However, the signals that drive the specific intracellular localization of syntaxins are poorly understood. In this study, we used indirect immunofluorescence analysis to examine the localization of syntaxin… CONTINUE READING
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