Roles of the cilium-associated gene CCDC11 in left-right patterning and in laterality disorders in humans.

@article{Gur2017RolesOT,
  title={Roles of the cilium-associated gene CCDC11 in left-right patterning and in laterality disorders in humans.},
  author={Michal Gur and E. B. Cohen and O. Genin and A. Fainsod and Z. Perles and Y. Cinnamon},
  journal={The International journal of developmental biology},
  year={2017},
  volume={61 3-4-5},
  pages={
          267-276
        }
}
Axial determination occurs during early stages of embryogenesis. Flaws in laterality patterning result in abnormal positioning of visceral organs, as manifested in heterotaxy syndrome, or complete left-right inversion as in situs inversus totalis. These malformations are often associated with ciliopathies, as seen in primary ciliary dyskinesia. We have recently described a novel mutation in the Coiled-Coil Domain-Containing 11 (CCDC11) gene associated with laterality disorders in a… Expand
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The Cilium- and Centrosome-Associated Protein CCDC11 Is Required for Cytokinesis via Midbody Recruitment of the ESCRT- III Membrane Scission Complex Subunit CHMP2A
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CCDC114, DNAI2 and TOP2A involves in the effects of tibolone treatment on postmenopausal endometrium
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