Roles of the Yfe and Feo transporters of Yersinia pestis in iron uptake and intracellular growth

@article{Perry2006RolesOT,
  title={Roles of the Yfe and Feo transporters of Yersinia pestis in iron uptake and intracellular growth},
  author={Robert D. Perry and Ildefonso Mier and Jacqueline D. Fetherston},
  journal={BioMetals},
  year={2006},
  volume={20},
  pages={699-703}
}
In Yersinia pestis, the Yfe and Feo systems likely function to transport ferrous iron. Both FeoA and FeoB are essential for iron acquisition activity while FeoC is not. Mutations in yfe and feo had an additive effect on microaerophilic growth under iron-chelating conditions. Y. pestis cells lacking the Ybt siderophore-dependent system, the Yfe or the Feo system grow normally in J774A.1 cells. However, a double yfeAB feoB mutant was no longer able to grow in this murine macrophage cell line… CONTINUE READING
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