Corpus ID: 33955727

Roles of the VMA3 gene product, subunit c of the vacuolar membrane H(+)-ATPase on vacuolar acidification and protein transport. A study with VMA3-disrupted mutants of Saccharomyces cerevisiae.

@article{Umemoto1990RolesOT,
  title={Roles of the VMA3 gene product, subunit c of the vacuolar membrane H(+)-ATPase on vacuolar acidification and protein transport. A study with VMA3-disrupted mutants of Saccharomyces cerevisiae.},
  author={Naoyuki Umemoto and Takaishi Yoshihisa and Roli Hirata and Yasuhiro Anraku},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 30},
  pages={
          18447-53
        }
}
  • Naoyuki Umemoto, Takaishi Yoshihisa, +1 author Yasuhiro Anraku
  • Published in
    The Journal of biological…
    1990
  • Biology, Medicine
  • VMA3, a structure gene of the vacuolar membrane H(+)-ATPase subunit c of Saccharomyces cerevisiae, has been cloned and characterized. The VMA3 gene encodes a hydrophobic polypeptide with 160 amino acids as reported previously by Nelson and Nelson (Nelson, H., and Nelson, N. (1989) FEBS Lett. 247, 147-153). Peptide sequence analysis indicated that the VMA3 gene product lacks N-terminal methionine and does not have a cleavable signal sequence. To investigate functional and structural roles of the… CONTINUE READING

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